Fabrication of PLGA nanoparticles with a fluidic nanoprecipitation system
نویسندگان
چکیده
منابع مشابه
Fabrication of PLGA nanoparticles with a fluidic nanoprecipitation system
Particle size is a key feature in determining performance of nanoparticles as drug carriers because it influences circulating half-life, cellular uptake and biodistribution. Because the size of particles has such a major impact on their performance, the uniformity of the particle population is also a significant factor. Particles comprised of the polymer poly(lactic-co-glycolic acid) (PLGA) are...
متن کاملFabrication and in vitro evaluation of Ketotifen Fumarate-loaded PLGA nanoparticles as a sustained delivery system
Abstract Ketotifen fumarate is a non-bronchodilator anti-asthmatic drug which inhibits the effects of certain endogenous substances known to be inflammatory mediators, and thereby exerts antiallergic activity. The present study describes the formulation of a sustained release nanoparticle (NP) drug delivery system containing ketotifen, using poly (D,L lactide-co-glycolide acid) (PLGA). Biodegra...
متن کاملFabrication and in vitro evaluation of Ketotifen Fumarate-loaded PLGA nanoparticles as a sustained delivery system
Abstract Ketotifen fumarate is a non-bronchodilator anti-asthmatic drug which inhibits the effects of certain endogenous substances known to be inflammatory mediators, and thereby exerts antiallergic activity. The present study describes the formulation of a sustained release nanoparticle (NP) drug delivery system containing ketotifen, using poly (D,L lactide-co-glycolide acid) (PLGA). Biodegra...
متن کاملfabrication and in vitro evaluation of ketotifen fumarate-loaded plga nanoparticles as a sustained delivery system
abstract ketotifen fumarate is a non-bronchodilator anti-asthmatic drug which inhibits the effects of certain endogenous substances known to be inflammatory mediators, and thereby exerts antiallergic activity. the present study describes the formulation of a sustained release nanoparticle (np) drug delivery system containing ketotifen, using poly (d,l lactide-co-glycolide acid) (plga). biodegra...
متن کاملFabrication and in-vitro Evaluation of Ketotifen Fumarate-loaded PLGA Nanoparticles as a Sustained Delivery System
Ketotifen fumarate is a non-bronchodilator anti-asthmatic drug which inhibits the effects of certain endogenous substances known to be inflammatory mediators, and thereby exerts antiallergic activity. The present study describes the formulation of a sustained release nanoparticle (NP) drug delivery system containing ketoftifen, using poly (D,L lactide-co-glycolide) acid (PLGA). Biodegradable NP...
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ژورنال
عنوان ژورنال: Journal of Nanobiotechnology
سال: 2010
ISSN: 1477-3155
DOI: 10.1186/1477-3155-8-18